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Mouse monoclonal antibody

Anti-Oxyntomodulin (human)

CAT NO: ABS 059-20 | Application: ELISA


Cat. No.

ABS 059-20

Specificity

ABS 059-20 is specific for human oxyntomodulin. Cross-reacts fully with glucagon.

Immunogen

Synthetic full length oxyntomodulin coupled to carrier.

Host

Mouse

Positive Species Reactivity

Human

Negative Species Reactivity

Not determined

Isotype

IgG1/k

Gene ID

2641

Clone Number

20

Epitope Specificity

ABS 059-20 has a different epitope specificity than ABS 064-46 and ABS 064-23.

Unit Size

400 µL: Cat. No. ABS 059-20-04 1 mL: Cat. No. ABS 059-20-1 1 mg/mL +/- 15%. See Certificate of Analysis for details.

Purification

Protein A/G purified (from culture supernatant)

Form

Liquid

Solvent

0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide

Conjugation

Unconjugated BSA free

Storage

2-8ºC without exposure to light. No precautions necessary during handling.

Target

Oxyntomodulin is a peptide hormone of 37 amino-acid residues (29-amino acid sequence of glucagon, with an 8-amino acid carboxy-terminal extension) produced by the L cells of the gut. It modulates gastric acid secretion from the oxyntic cells of the stomach, inhibits appetite and has glucose lowering effects. Oxyntomodulin is produced by cell-type-specific processing of proglucagon that forms as well glicentin, GLP-1 and GLP-2 in the L cells of the intestinal mucosa.