Product Summary

Cat. No.
ABS 064-46
Specificity
ABS 064-46 is specific for C-terminus of human oxyntomodulin. Does not cross-react with glucagon.
Immunogen
Synthetic oxyntomodulin 31-37 coupled to carrier.
Host
Mouse
Positive Species Reactivity
Human, Mouse, Rat
Negative Species Reactivity
Not determined
Isotype
IgG1/k
Gene ID
2641
Clone Number
46
Epitope Specificity
ABS 064-46 has a different epitope specificity compared to ABS 064-23 and ABS 059-20.
Unit Size
400 µL: Cat. No. ABS 064-46-04 1 mL: Cat. No. ABS 064-46-1 1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification
protein A/G purified (from culture supernatant)
Form
Liquid
Solvent
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Conjugation
Unconjugated BSA free
Storage
2-8ºC
Target
Oxyntomodulin is a peptide hormone of 37 amino-acid residues (29-amino acid sequence of glucagon, with an 8-amino acid carboxy-terminal extension) produced by the L cells of the gut. It modulates gastric acid secretion from the oxyntic cells of the stomach, inhibits appetite and has glucose lowering effects. Oxyntomodulin is produced by cell-type-specific processing of proglucagon that forms as well glicentin, GLP-1 and GLP-2 in the L cells of the intestinal mucosa.

Application

ELISA: ABS 064-46 (as capture antibody) forms a sandwich ELISA pair with ABS 059-20B (as biotinylated detection antibody) for measuring Oxyntomodulin. ABS 064-46 is specific for oxyntomodulin and does not cross-react with glucagon.

Cat. No.
ABS 064-46
Specificity
ABS 064-46 is specific for C-terminus of human oxyntomodulin. Does not cross-react with glucagon.
Immunogen
Synthetic oxyntomodulin 31-37 coupled to carrier.
Host
Mouse
Positive Species Reactivity
Human, Mouse, Rat
Negative Species Reactivity
Not determined
Isotype
IgG1/k
Gene ID
2641
Clone Number
46
Epitope Specificity
ABS 064-46 has a different epitope specificity compared to ABS 064-23 and ABS 059-20.
Unit Size
400 µL: Cat. No. ABS 064-46-04 1 mL: Cat. No. ABS 064-46-1 1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification
protein A/G purified (from culture supernatant)
Form
Liquid
Solvent
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Conjugation
Unconjugated BSA free
Storage
2-8ºC
Target
Oxyntomodulin is a peptide hormone of 37 amino-acid residues (29-amino acid sequence of glucagon, with an 8-amino acid carboxy-terminal extension) produced by the L cells of the gut. It modulates gastric acid secretion from the oxyntic cells of the stomach, inhibits appetite and has glucose lowering effects. Oxyntomodulin is produced by cell-type-specific processing of proglucagon that forms as well glicentin, GLP-1 and GLP-2 in the L cells of the intestinal mucosa.

ELISA: ABS 064-46 (as capture antibody) forms a sandwich ELISA pair with ABS 059-20B (as biotinylated detection antibody) for measuring Oxyntomodulin. ABS 064-46 is specific for oxyntomodulin and does not cross-react with glucagon.

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