Mouse monoclonal antibody, biotinylated
Anti-Oxyntomodulin (human)
CAT NO: ABS 059-20B | Application: ELISA
Cat. No.  | 
        ABS 059-20B  | 
      
|---|---|
Specificity  | 
            ABS 059-20 is specific for human oxyntomodulin. Cross-reacts fully with glucagon.  | 
          
Immunogen  | 
            Synthetic full length oxyntomodulin coupled to carrier.  | 
          
Host  | 
            Mouse  | 
          
Positive Species Reactivity  | 
            Human, Mouse, Rat  | 
          
Negative Species Reactivity  | 
            Not determined  | 
          
Isotype  | 
            IgG1/k  | 
          
Gene ID  | 
            2641  | 
          
Clone Number  | 
            20  | 
          
Epitope Specificity  | 
            ABS 059-20 has a different epitope specificity than ABS 064-46 and ABS 064-23.  | 
          
Unit Size  | 
            150 µL: Cat. No. ABS 059-20B-015 1 mg/mL +/- 15%. See Certificate of Analysis for details.  | 
          
Purification  | 
            Biotinylated  | 
          
Form  | 
            Liquid  | 
          
Solvent  | 
            0.01 M phosphate buffer, pH 7.4, with 0.14 M NaCl and 15mM sodium azide  | 
          
Conjugation  | 
            Biotin  | 
          
Storage  | 
            2-8ºC without exposure to light. No precautions necessary during handling.  | 
          
Target  | 
            Oxyntomodulin is a peptide hormone of 37 amino-acid residues (29-amino acid sequence of glucagon, with an 8-amino acid carboxy-terminal extension) produced by the L cells of the gut. It modulates gastric acid secretion from the oxyntic cells of the stomach, inhibits appetite and has glucose lowering effects. Oxyntomodulin is produced by cell-type-specific processing of proglucagon that forms as well glicentin, GLP-1 and GLP-2 in the L cells of the intestinal mucosa.  |