Mouse monoclonal antibody, biotinylated
Anti-Ghrelin (human, rat)
CAT NO: ABS 052-121B | Application: ELISA
Cat. No. |
ABS 052-121B |
---|---|
Specificity |
ABS 052-121 binds human ghrelin. |
Immunogen |
Synthetic ghrelin (14-28) |
Host |
Mouse |
Positive Species Reactivity |
Human, Rat, Mouse, Dog, Cat |
Negative Species Reactivity |
Not determined |
Isotype |
IgG2b/k |
Gene ID |
51738, 59301 |
Clone Number |
121 |
Epitope Specificity |
Not determined |
Unit Size |
150 µL: Cat. No. ABS 052-121B-015 1 mg/mL +/- 15%. See Certificate of Analysis for details. |
Purification |
Biotinylated |
Form |
Liquid |
Solvent |
0.01 M phosphate buffer, pH 7.4, with 0.14 M NaCl and 15mM sodium azide |
Conjugation |
Biotin |
Storage |
4-8ºC without exposure to light. No precautions necessary during handling. |
Target |
Ghrelin is an orexigenic (food intake stimulating) 27 or 28 amino-acid gut-brain peptide hormone produced by endocrine cells in the stomach, pancreatic islets and certain hypothalamic neurons. Two forms are produced by alternative mRNA splicing; Gln13 or 14 is missing from the second form. "Active" ghrelin is acylated (octanoylated) at Ser3; this form stimulates growth hormone secretion via GHS receptors and increases appetite. The des-acyl form does not have these effects but may have other actions. Plasma responses of total ghrelin to food reflect those of active ghrelin. |