Mouse monoclonal antibody, biotinylated

Anti-Peptide YY (human, PYY)

CAT NO: ABS 029-01B | Application: ELISA

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Product Summary

Cat. No.
ABS 029-01B
Specificity
ABS 029-01 binds human PYY. Cross-reactivity with NPY or PP in solution is <0.1%.
Immunogen
Synthetic human PYY
Host
Mouse
Positive Species Reactivity
Human
Negative Species Reactivity
Not determined
Isotype
IgG1/k
Gene ID
5697
Clone Number
1
Epitope Specificity
Not determined
Unit Size
150 µL: Cat. No. ABS 029-01B-015 1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification
Biotinylated
Form
Liquid
Solvent
0.01 M phosphate buffer, pH 7.4, with 0.14 M NaCl and 15mM sodium azide
Conjugation
Biotin
Storage
4-8ºC without exposure to light. No precautions necessary during handling.
Target
Peptide tyrosine-tyrosine (PYY) amide is a 36 amino acid. PYY is a member of the pancreatic polypeptide (PP) family of peptides (neuropeptide Y (NPY), PYY and PP). While NPY is localized in neurons (both in the central and peripheral nervous system) and PP in the pancreatic islets, PYY is found in both neurons and the gut. PYY is released in response to food intake from the same endocrine cells (L cells) in the intestinal mucosa as the glucagon-like peptides and inhibits gall bladder secretion, gut motility, and pancreatic secretion. These effects are similar to those of PP and overlap with the gut inhibitory activity of GLP-1.

Application

ELISA: Biotinylated ABS 029-01 can be used as a detection antibody with ABS 051-04 as a capture antibody for measuring PYY(3-36) by sandwich ELISA.

Cat. No.
ABS 029-01B
Specificity
ABS 029-01 binds human PYY. Cross-reactivity with NPY or PP in solution is <0.1%.
Immunogen
Synthetic human PYY
Host
Mouse
Positive Species Reactivity
Human
Negative Species Reactivity
Not determined
Isotype
IgG1/k
Gene ID
5697
Clone Number
1
Epitope Specificity
Not determined
Unit Size
150 µL: Cat. No. ABS 029-01B-015 1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification
Biotinylated
Form
Liquid
Solvent
0.01 M phosphate buffer, pH 7.4, with 0.14 M NaCl and 15mM sodium azide
Conjugation
Biotin
Storage
4-8ºC without exposure to light. No precautions necessary during handling.
Target
Peptide tyrosine-tyrosine (PYY) amide is a 36 amino acid. PYY is a member of the pancreatic polypeptide (PP) family of peptides (neuropeptide Y (NPY), PYY and PP). While NPY is localized in neurons (both in the central and peripheral nervous system) and PP in the pancreatic islets, PYY is found in both neurons and the gut. PYY is released in response to food intake from the same endocrine cells (L cells) in the intestinal mucosa as the glucagon-like peptides and inhibits gall bladder secretion, gut motility, and pancreatic secretion. These effects are similar to those of PP and overlap with the gut inhibitory activity of GLP-1.

ELISA: Biotinylated ABS 029-01 can be used as a detection antibody with ABS 051-04 as a capture antibody for measuring PYY(3-36) by sandwich ELISA.

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Product Specification

Non-hazardous statement (SDS)

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