Mouse monoclonal antibody, biotinylated
Anti-Peptide YY (human, PYY)
CAT NO: ABS 029-01B | Application: ELISA
Cat. No. |
ABS 029-01B |
---|---|
Specificity |
ABS 029-01 binds human PYY. Cross-reactivity with NPY or PP in solution is <0.1%. |
Immunogen |
Synthetic human PYY |
Host |
Mouse |
Positive Species Reactivity |
Human |
Negative Species Reactivity |
Not determined |
Isotype |
IgG1/k |
Gene ID |
5697 |
Clone Number |
1 |
Epitope Specificity |
Not determined |
Unit Size |
150 µL: Cat. No. ABS 029-01B-015 1 mg/mL +/- 15%. See Certificate of Analysis for details. |
Purification |
Biotinylated |
Form |
Liquid |
Solvent |
0.01 M phosphate buffer, pH 7.4, with 0.14 M NaCl and 15mM sodium azide |
Conjugation |
Biotin |
Storage |
4-8ºC without exposure to light. No precautions necessary during handling. |
Target |
Peptide tyrosine-tyrosine (PYY) amide is a 36 amino acid. PYY is a member of the pancreatic polypeptide (PP) family of peptides (neuropeptide Y (NPY), PYY and PP). While NPY is localized in neurons (both in the central and peripheral nervous system) and PP in the pancreatic islets, PYY is found in both neurons and the gut. PYY is released in response to food intake from the same endocrine cells (L cells) in the intestinal mucosa as the glucagon-like peptides and inhibits gall bladder secretion, gut motility, and pancreatic secretion. These effects are similar to those of PP and overlap with the gut inhibitory activity of GLP-1. |