Mouse monoclonal antibody

Anti-Glucagon (human, pig, rat)

CAT NO: ABS 061-09 | Application: ELISA, IHC, IF

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Cat. No.	ABS 061-09
Specificity	ABS 061-09 binds human glucagon. Cross-reacts less than 5% with oxyntomodulin.
Immunogen	Synthetic full length oxyntomodulin coupled to carrier.
Host	Mouse
Positive Species Reactivity	Human, Rat, Pig
Negative Species Reactivity	Not determined
Isotype	IgG1/k
Gene ID	2641, 24952, 397595
Clone Number	9
Epitope Specificity	The epitope lies within the C-terminal region of glucagon.
Unit Size	400 µL: Cat. No. ABS 061-09-04 1 mL: Cat. No. ABS 061-09-1 1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification	protein A/G purified (from culture supernatant)
Form	Liquid
Solvent	0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Conjugation	Unconjugated BSA free
Storage	4-8ºC without exposure to light. No precautions necessary during handling.
Target	Glucagon is a peptide hormone of 29 amino-acid residues produced by the alpha cells of the pancreatic islets. Its effect is to raise blood sugar as a stress hormone and counter-regulatory hormone for insulin. It is produced by cell-type-specific processing of proglucagon, which in the alpha cells is split to form glicentin-related pancreatic polypeptide, glucagon and major proglucagon fragment, while the same precursor is split to form glicentin, oxyntomodulin (C-terminally extended glucagon-37), GLP-1 and GLP-2 in the L cells of the intestinal mucosa.