| Specificity |
ABS 061-09 binds human glucagon. Cross-reacts less than 5% with oxyntomodulin.The epitope lies within the C-terminal region of glucagon. |
| Immunogen |
Synthetic C-terminal fragment of glucagon coupled to carrier |
| Target |
Glucagon is a peptide hormone of 29 amino-acid residues produced by the alpha cells of the pancreatic islets. Its effect is to raise blood sugar as a stress hormone and counter-regulatory hormone for insulin. It is produced by cell-type-specific processing of proglucagon, which in the alpha cells is split to form glicentin-related pancreatic polypeptide, glucagon and major proglucagon fragment, while the same precursor is split to form glicentin, oxyntomodulin (C-terminally extended glucagon-37), GLP-1 and GLP-2 in the L cells of the intestinal mucosa. |
| Gene ID |
2641, 24952, 397595 |
| Species Reactivity POSITIVE |
Human, Rat, Pig |
| Species Reactivity NEGATIVE |
Not determined |
