Mouse monoclonal antibody

Anti-PYY(3-36) (peptide tyrosine-tyrosine amide, 3-36)

CAT NO: ABS 051-04 | Application: ELISA, WB

Request Price

"*" indicates required fields

Name*

First Last

Email*

Phone

Organization

Shipping Address*

City, State, Post Code/Zip*

Country*

States*

Catalog Number ( Product )

Message

This field is for validation purposes and should be left unchanged.

Cat. No.	ABS 051-04
Specificity	ABS 051-04 binds human PYY(3-36). Based on inhibition ELISA, ABS 051-04 shows no cross-reaction with PYY(1-36) or NPY.
Immunogen	Synthetic N-terminal fragment of human PYY(3-36) coupled to carrier.
Host	Mouse
Positive Species Reactivity	Human
Negative Species Reactivity	Mouse, Rat, Dog, Pig
Isotype	IgG2a/k
Gene ID	5697
Clone Number	4
Epitope Specificity	The epitope lies within residues 3-12 of human PYY.
Unit Size	400 µL: Cat. No. ABS 051-04-04 1 mL: Cat. No. ABS 051-04-1 1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification	Protein A/G purified (from culture supernatant)
Form	Liquid
Solvent	0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Conjugation	Unconjugated BSA free
Storage	4-8ºC without exposure to light. No precautions necessary during handling.
Target	Peptide tyrosine-tyrosine amide (3-36), or PYY(3-36), is a major metabolite of the gut hormone PYY and is produced by the action of dipeptidyl peptidase IV on PYY in the intestinal brush border and in the circulation. PYY(3-36) is a potent inhibitor of food intake in rats and humans, acting selectively on the Y2 receptor to inhibit orexigenic NPY neurons in the arcuate nucleus, thus disinhibiting anorexigenic POMC neurons. The anorexigenic effect of PYY(3-36) is additive to that of the co-secreted gut hormone GLP-1.