Mouse monoclonal antibody

Anti-Peptide YY (human, PYY)

CAT NO: ABS 029-01 | Application: ELISA, IHC

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Cat. No.	ABS 029-01
Specificity	ABS 029-01 binds human PYY. Cross-reactivity with NPY or PP in solution is <0.1%.
Immunogen	Synthetic human PYY
Host	Mouse
Positive Species Reactivity	Human
Negative Species Reactivity	Not determined
Isotype	IgG1/k
Gene ID	5697
Clone Number	1
Epitope Specificity	Not determined
Unit Size	400 µL: Cat. No. ABS 029-01-04 1 mL: Cat. No. ABS 029-01-1 1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification	Protein A/G purified (from culture supernatant)
Form	Liquid
Solvent	0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Conjugation	Unconjugated BSA free
Storage	4-8ºC without exposure to light. No precautions necessary during handling.
Target	Peptide tyrosine-tyrosine (PYY) amide is a 36 amino acid. PYY is a member of the pancreatic polypeptide (PP) family of peptides (neuropeptide Y (NPY), PYY and PP). While NPY is localized in neurons (both in the central and peripheral nervous system) and PP in the pancreatic islets, PYY is found in both neurons and the gut. PYY is released in response to food intake from the same endocrine cells (L cells) in the intestinal mucosa as the glucagon-like peptides and inhibits gall bladder secretion, gut motility, and pancreatic secretion. These effects are similar to those of PP and overlap with the gut inhibitory activity of GLP-1.